Vitamin K1 Impurity 2 CAS 15576-40-6
| CAS No. | 15576-40-6 |
| Molecular Formula | C31H46O3 |
| Molecular Weight | 466.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Vitamin K1 Impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Vitamin K1 Impurity 2 (CAS 15576-40-6) is a certified pharmaceutical impurity reference standard with the molecular formula C31H46O3 and a molecular weight of 466.70 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H46O3 |
| Molecular Weight | 466.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Vitamin Standards
- Vitamin K1 Impurity 34 (CAS CATO-C4X-220734)
- Vitamin K1 Impurity 43 (CAS 1181-23-3)
- Vitamin K1-d7 2,3-Epoxide (CAS 1795136-97-8)
- Vitamin K1 D7 ( Mixture of Cis & Trans) (CAS CATO-C4X-2207102)
- cis-Vitamin K1 D7 (CAS CATO-C4X-2207103)
- cis-Vitamin K1-d7 (CAS 16033-41-3 (non-labelled))
- Vitamin K1-d7 (CAS 1233937-39-7)
- Vitamin A impurity 26 (CAS CATO-C4X-218726)
Recommended Standards
- All-Rac-Phytomenadione EP Impurity B (CAS 25486-55-9)
- (2R,3S)-Epoxide Vitamin K1 (CAS 85955-78-8)
- Phytonadione Epoxide (CAS 41018-27-3)
- (2S,3R)-Epoxide Vitamin K1 (CAS CATO-C4X-220724)
- Dapagliflozin Impurity 110 (CAS CATO-C4X-1138110)
- Ceftazidime Impurity 52 (CAS CATO-C4X-121252)
- Brexpiprazole Impurity 110 (CAS 433303-94-7)
- (R)-3-Amino-5-(1-aminoethyl)benzonitrile (CAS 2789706-25-6)
- 3-Amino-2,4-difluorobenzoic acid (CAS 1512022-61-5)
- 6-Cyclohexyl-4-methyl-2H-pyran-2-one-d11 (CAS 1794737-30-6)
- (S)-(1-Bromo-2-propyl)benzene (CAS 147514-19-0)
- 5-(3-Bromophenyl)-3-(chloromethyl)-1,2,4-oxadiazole (CAS 657423-61-5)
- 4-Phenyl-3-{1-[4-(trifluoromethoxy)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775532-51-8)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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