tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate CAS 1557780-95-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1557780-95-6
Molecular FormulaC13H13ClINO2
Molecular Weight377.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate CAS 1557780-95-6 chemical structure

Description

The occurrence of tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate (CAS 1557780-95-6), a certified reference material (molecular formula C13H13ClINO2, MW 377.61 g/mol) for analytical method development and quality control.

The molecular framework of tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate (C13H13ClINO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), tert-Butyl 6-chloro-3-iodo-1H-indole-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H13ClINO2
Molecular Weight377.61 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl/I-containing
Nitrogen Atoms1

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