1-(5-Fluoro-1H-indol-2-yl)-N-methylmethanamine hemisulfate CAS 1559059-72-1
| CAS No. | 1559059-72-1 |
| Molecular Formula | C10H11FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Fluoro-1H-indol-2-yl)-N-methylmethanamine hemisulfate (CAS 1559059-72-1) is a high-purity analytical reference standard with the molecular formula C10H11FN2H2O4S and a molecular weight of 276.28 g/mol.
The molecular framework of 1-(5-Fluoro-1H-indol-2-yl)-N-methylmethanamine hemisulfate (C10H11FN2H2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11FN2 H2O4S |
| Molecular Weight | 276.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 2-methyl-2H,4H,5H,6H-cyclopenta[c]pyrazole-5-carboxylic acid (CAS 1780282-55-4)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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