Diethyl (difluoro(4-iodophenyl)methyl)phosphonate CAS 156017-41-3
| CAS No. | 156017-41-3 |
| Molecular Formula | C11H14F2IO3P |
| Molecular Weight | 390.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diethyl (difluoro(4-iodophenyl)methyl)phosphonate (CAS 156017-41-3) is a high-purity analytical reference standard with the molecular formula C11H14F2IO3P and a molecular weight of 390.10 g/mol.
The molecular framework of Diethyl (difluoro(4-iodophenyl)methyl)phosphonate (C11H14F2IO3P) is characterized by a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Diethyl (difluoro(4-iodophenyl)methyl)phosphonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14F2IO3P |
| Molecular Weight | 390.10 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F/I-containing |
Related Diethyl Standards
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Recommended Standards
- 5-Iodo-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzonitrile (CAS 1369255-12-8)
- 2H,3h-perfluoronon-2-enoic acid (CAS 243139-70-0)
- 4,5-Dibromo-N-(1-(pyridin-3-yl)ethyl)thiophene-2-carboxamide (CAS 877987-93-4)
- 4,4-Bis(trifluoromethyl)-5,5,6,6,7,7,7-heptafluorohept-2-enoic acid (CAS 261503-43-9)
- 2-(4-amino-1H-pyrazol-1-yl)acetohydrazide hydrochloride,HCl (CAS 1171032-42-0)
- 4-(5-Bromo-6-methyl-2-pyridinyl)morpholine (CAS 1199773-21-1)
- 2-Bromo-3,4-difluoro-1-methylbenzene (CAS 1807187-70-7)
- 4-Bromo-2-(difluoromethyl)-5-methyl-3-(trifluoromethyl)pyridine (CAS 1804429-71-7)
- 5,7-Difluoro-2-methylbenzo[d]thiazole (CAS 1188093-52-8)
- Methyl (3R)-3-aminohex-5-enoate hydrochloride (CAS 1820571-33-2)
- 1-(2-Methylazulen-1-yl)ethanone (CAS 105903-83-1)
- 1-chloro-2-(dichloromethyl)-3-fluorobenzene (CAS 62476-62-4)
- N-(1-Cyanocyclohexyl)-2-((5-(pyridin-4-yl)-4-(o-tolyl)-4H-1,2,4-triazol-3-yl)thio)propanamide (CAS 852687-65-1)
- Lixisenatide (CAS 320367-13-3)
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