7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel CAS 156413-61-5
| CAS No. | 156413-61-5 |
| Molecular Formula | C59H79NO14Si2 |
| Molecular Weight | 1082.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel (CAS 156413-61-5), molecular formula C59H79NO14Si2 and molecular weight 1082.43 g/mol, is a CATO reference standard with documented purity and traceability.
7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel (C59H79NO14Si2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C59H79NO14Si2 |
| Molecular Weight | 1082.43 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 1 |
Related O Standards
- 7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl 2-Debenzoyl Paclitaxel 2-Pentanoate (CAS 1055033-93-6)
- 7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel (CAS 162459-94-1)
- 7,10,13-Tris(triethylsilyl)-10-Deacetylbaccatin III (CAS 194720-19-9)
- 7-Triethylsilyl-13-oxobaccatin III (CAS 150665-56-8)
- 7-O-(Triethylsilyl)-10-deacetyl Baccatin III (CAS 115437-18-8)
- 10-(Triethylsilyl)benzo[lmn]thieno[2,3-f][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (CAS 2195419-19-1)
- N-(3-(Triethylsilyl)propyl)quinolin-4-amine (CAS 62619-93-6)
- Triethylsilyl 2,2-difluoro-2-(fluorosulfonyl)acetate (CAS 757203-27-3)
Recommended Standards
- Azalomycin F4 (CAS 81545-42-8)
- Lifitegrast Impurity 47 (CAS CATO-C4X-240947)
- 7-aminomethyl-7- deazaguanosine Phosphoramidite (CAS CATO-C4X-288615)
- N-{[({[(1S)-1-[({[({[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0²,¹⁴.0⁴,¹³.0⁶,¹¹.0²⁰,²⁴]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]carbamoyl}methoxy)methyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}methyl)carbamoyl]methyl}-4,7,10,13-tetraoxahexadec-15-ynamide (CAS 2762518-94-3)
- Dextromethorphan N-Oxide（HCl） (CAS 1177419-85-0)
- β-Rotunol (CAS 24405-57-0)
- 5-[(3-methoxyphenyl)methyl]-1,3,4-oxadiazol-2-amine (CAS 1016691-89-6)
- Dopaquinone Lactone (CAS 255829-51-7)
- 7H-Spiro[furo[3,4-b]pyridine-5,3'-pyrrolidin]-7-one (CAS 869969-57-3)
- 6-Methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one (CAS 54401-47-7)
- Methyl 2-(4-(4-hydroxybutyl)phenyl)-2-methylpropanoate (CAS 154825-93-1)
- Ethyl 1-(1-methylcyclohexyl)-1H-pyrazole-4-carboxylate (CAS 2504239-22-7)
- 2-(2,4-Dimethylphenoxy)aniline 60287-72-1 6507AE C14H15NO (CAS 60287-72-1)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com