(2`R,2S,cis)-Saxagliptin CAS 1564265-93-5
| CAS No. | 1564265-93-5 |
| Molecular Formula | C18H25N3O2 |
| Molecular Weight | 315.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, (2`R,2S,cis)-Saxagliptin (CAS 1564265-93-5, C18H25N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
(2`R,2S,cis)-Saxagliptin (C18H25N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures (2`R,2S,cis)-Saxagliptin under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H25N3O2 |
| Molecular Weight | 315.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 3 |
Recommended Standards
- Saxagliptin Impurity 13 (CAS CATO-C4X-104913)
- Saxagliptin Impurity 3 (CAS 1564265-96-8)
- Saxagliptin Impurity 12 (CAS 1564265-94-6)
- Saxagliptin Impurity 4 (CAS 1564266-00-7)
- Voriconazole Impurity 82 (CAS CATO-C4X-136682)
- Simvastatin EP Impurity D (CAS 476305-24-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com