4-(chloromethyl)-3-fluorobenzoic acid CAS 1565375-97-4
| CAS No. | 1565375-97-4 |
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(chloromethyl)-3-fluorobenzoic acid.
4-(chloromethyl)-3-fluorobenzoic acid (CAS 1565375-97-4), molecular formula C8H6ClFO2 and molecular weight 188.58 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H6ClFO2, 4-(chloromethyl)-3-fluorobenzoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO2 |
| Molecular Weight | 188.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
Related chloromethyl Standards
- 6-(Chloromethyl)-4-fluorobenzo[d][1,3]dioxole (CAS 945244-10-0)
- 2-(Chloromethyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid (CAS 1934972-12-9)
- 1-(1-Chloromethyl-vinyl)-2,4-difluoro-benzene (CAS 156570-10-4)
- Ethyl 1-(chloromethyl)-1H-pyrazole-3-carboxylate (CAS 1006455-27-1)
- 3-(Chloromethyl)-5-(tetrahydrofuran-2-yl)-1,2,4-oxadiazole (CAS 1039860-29-1)
- 5-Chloromethyl-2-methyl-2H-pyrazole-3-carboxylicacid methyl ester (CAS 1208081-34-8)
- 2-(Chloromethyl)-5-(oxolan-3-yl)-1,3,4-oxadiazole (CAS 1250108-14-5)
- Ethyl 3-(chloromethyl)-1H-pyrazole-4-carboxylate (CAS 137487-60-6)
Recommended Standards
- 3-Chloro-2-fluoro-5-methoxybenzaldehyde (CAS 1557177-77-1)
- 4-Chloro-3-fluoro-2-methylbenzoic acid (CAS 157652-29-4)
- 4-Chloro-3-fluoro-2-methoxybenzaldehyde (CAS 1554658-43-3)
- 3-Chloro-6-fluoro-2-methoxybenzaldehyde (CAS 1646821-91-1)
- Methyl 5-chloro-6-(trifluoromethyl)pyrazine-2-carboxylate (CAS 1688685-61-1)
- 1-((4-Bromophenoxy)methyl)-3,5-dimethyl-1H-pyrazol-4-amine (CAS 1006457-23-3)
- 2-(((Benzyloxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid (CAS 55478-54-1)
- Ethyl 4-(dimethylamino)-3-nitrobenzoate (CAS 40700-40-1)
- 2,2,4-Trimethyl-2,3-dihydro-1-benzofuran-7-amine (CAS 756431-31-9)
- Diflunisal impurity 5 (CAS 53591-79-0)
- 5-(4-Fluorophenyl)-1-methyl-3-propyl-1H-1,2,4-triazole (CAS 915303-67-2)
- 3330AF 6-(Difluoromethyl)-4-methyl-1H-pyrazolo[3,4-b]-pyridin-3-amine 925146-05-0 C8H8F2N4 (CAS 925146-05-0)
- tert-Butyl (2-bromo-5-chlorothiophen-3-yl)carbamate (CAS 2567558-82-9)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
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