(2-Chloro-6-fluorophenyl)(3-methylpiperazin-1-yl)methanone CAS 1569043-96-4
| CAS No. | 1569043-96-4 |
| Molecular Formula | C12H14ClFN2O |
| Molecular Weight | 256.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2-Chloro-6-fluorophenyl)(3-methylpiperazin-1-yl)methanone (CAS 1569043-96-4), molecular formula C12H14ClFN2O and molecular weight 256.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2-Chloro-6-fluorophenyl)(3-methylpiperazin-1-yl)methanone is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 256.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), (2-Chloro-6-fluorophenyl)(3-methylpiperazin-1-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClFN2O |
| Molecular Weight | 256.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(4-Chloro-2-fluorobenzoyl)-1,4-diazepane (CAS 1016756-97-0)
- N-(3-chloro-4-fluorophenyl)piperidine-4-carboxamide (CAS 1039868-09-1)
- 1-(4-Chloro-2-fluorobenzoyl)-3-methylpiperazine (CAS 1240565-13-2)
- 1-(4-Chloro-2-fluorobenzoyl)-2-methylpiperazine (CAS 1240573-92-5)
- 2-chloro-4-methyl-7-(trifluoromethyl)quinazoline (CAS 1388055-42-2)
- 3-chloro-2-methyl-6-(trifluoromethyl)quinoxaline (CAS 166402-14-8)
- 2-Chloro-4-fluoro-N-methyl-N-(pyrrolidin-3-yl)benzamide (CAS 1826187-88-5)
- 1-(2-Chloro-4-fluorophenyl)cyclohexane-1-carboxylic acid (CAS 214263-02-2)
Recommended Standards
- (4-Aminopiperidin-1-yl)(5-chloro-2-fluorophenyl)methanone hydrochloride (CAS 1583080-82-3)
- 2-Amino-N-(2-chloro-6-fluorobenzyl)-N-cyclopropylacetamide (CAS 1179691-77-0)
- (4-Aminopiperidin-1-yl)(2-chloro-4-fluorophenyl)methanone (CAS 1154258-30-6)
- 1-(2-Chloro-6-fluorophenyl)cyclohexane-1-carboxylic acid (CAS 214263-04-4)
- Ethyl 3-(thiophen-2-yl)propiolate (CAS 61354-73-2)
- N-(4-Aminophenyl)-2-(4-chlorophenoxy)acetamide (CAS 953717-19-6)
- 4-Chloro-6-[2-(1-methanesulfonyl-piperidin-2-yl)-ethyl]-pyrimidine (CAS 1316222-75-9)
- (S)-2-(3-(Benzyl(cyclopropyl)amino)pyrrolidin-1-yl)acetic acid (CAS 1354008-12-0)
- 5-Methyl-N-phenylisoxazole-4-carboxamide (CAS 134319-17-8)
- 3-Chloro-4-cyclopropoxypyridin-2-amine (CAS 1243459-09-7)
- 2,3-Dibromo-5-chlorobenzonitrile (CAS 1160574-35-5)
- 4,5-Dihydroxy-1,3-dimethyl-4,5-diphenylimidazolidin-2-one (CAS 66242-64-6)
- 2-Acetamido-2-(3,4-dichlorophenyl)propanoic acid (CAS 1406689-89-1)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
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