2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride CAS 157198-80-6

Purity 97%+In StockPharmaceutical Standards
CAS No.157198-80-6
Molecular FormulaC9H7ClN2O
Molecular Weight194.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride CAS 157198-80-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride.

2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride (CAS 157198-80-6) is a high-purity analytical reference standard with the molecular formula C9H7ClN2O and a molecular weight of 194.62 g/mol.

2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride (C9H7ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(1H-Benzo[d]imidazol-1-yl)acetyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H7ClN2O
Molecular Weight194.62 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2001
Halogen ContentCl-containing
Nitrogen Atoms2

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