7-(2,4-Dimethylphenyl)-2,5,6-trimethyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one CAS 157286-66-3
| CAS No. | 157286-66-3 |
| Molecular Formula | C17H19N3O |
| Molecular Weight | 281.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-(2,4-Dimethylphenyl)-2,5,6-trimethyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (C17H19N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
7-(2,4-Dimethylphenyl)-2,5,6-trimethyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 157286-66-3) is a high-purity analytical reference standard with the molecular formula C17H19N3O and a molecular weight of 281.35 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19N3O |
| Molecular Weight | 281.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 3 |
Related Dimethylphenyl Standards
- 7-(2,6-Dimethylphenyl)-2,5,6-trimethyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 157286-67-4)
- 4-[(2,4-Dimethylphenyl)methyl]-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 866157-84-8)
- (3Z)-3-{[(2,4-dimethylphenyl)amino]methylidene}-1,3-dihydro-2-benzothiophen-1-one (CAS 1164490-62-3)
- N-(2,6-Dimethylphenyl)-1H-benzo[d]imidazole-2-carbothioamide (CAS 1021208-03-6)
- 4-(3,4-Dimethylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine (CAS 1354935-93-5)
- 4-(3,4-Dimethylphenyl)-5-phenyl-4h-1,2,4-triazole-3-thiol (CAS 380191-03-7)
- 1-(3,4-Dimethylphenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxylic acid (CAS 1260950-82-0)
- 4-(3,4-Dimethylphenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1354704-94-1)
Recommended Standards
- [5-(1-Boc-4-piperidinyl)-1H-1,2,4-triazol-3-yl]methanamine (CAS 1546114-32-2)
- 3-Benzyl-2-butyl-3H-imidazo[4,5-c]pyridin-4(5H)-one (CAS 152460-59-8)
- N-[3-Cyano-4-methyl-1-(2,4,6-trimethyl-phenyl)-1H-pyrrol-2-yl]-acetamide (CAS 157286-79-8)
- Atazanavir Impurity 23 (CAS 149451-80-9)
- 5-Ethylthiophene-2-carboxylic acid (CAS 23229-72-3)
- 1-Aminoisoquinoline-7-carboxylic acid (CAS 221050-71-1)
- (3-(2,4-Dichlorophenyl)-1-(m-tolyl)-1H-pyrazol-4-yl)methanol (CAS 618441-89-7)
- (-)2'-epi-5-Deoxy-strigol (CAS 1259948-85-0)
- Chloropentaammineruthenium(II) chloride (CAS 137729-23-8)
- (E)-1-Chloro-4-(4-methoxystyryl)benzene (CAS 18878-89-2)
- 2,4-Dichloro-5-(trifluoromethoxy)aniline (CAS 1598-42-1)
- 2-(4-Bromothiophen-2-yl)-2-methyloxetane (CAS 1780308-52-2)
- (S)-5-(Methoxymethyl)pyrrolidin-2-one (CAS 129624-79-9)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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