4,6-Di-tert-butyl-2,2-dimethyl-2,3-dihydrobenzofuran-5-ol CAS 157360-02-6
| CAS No. | 157360-02-6 |
| Molecular Formula | C18H28O2 |
| Molecular Weight | 276.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,6-Di-tert-butyl-2,2-dimethyl-2,3-dihydrobenzofuran-5-ol.
4,6-Di-tert-butyl-2,2-dimethyl-2,3-dihydrobenzofuran-5-ol (CAS 157360-02-6), molecular formula C18H28O2 and molecular weight 276.41 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4,6-Di-tert-butyl-2,2-dimethyl-2,3-dihydrobenzofuran-5-ol (C18H28O2) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 276.41 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H28O2 |
| Molecular Weight | 276.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
Recommended Standards
- 1-(tert-Butyldimethylsilyl)-5-nitro-1H-indole (CAS 1558048-84-2)
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- 1-(4-(Decyloxy)phenyl)ethan-1-one (CAS 18099-59-7)
- 2-Amino-2-(3-bromo-4-fluorophenyl)acetic acid (CAS 299164-16-2)
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- tert-Butyl 4-bromo-2-chlorobenzyl(cyclopropyl)carbamate (CAS 1704074-34-9)
- Carazostatin (CAS 126168-32-9)
- 2-(4-Amino-1h-pyrazol-1-yl)-N,N-diethylpropanamide (CAS 1152513-49-9)
- Methyl 4-(4-methylpiperazino)-3-nitrobenzenecarboxylate (CAS 65715-48-2)
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- Semaglutide Impurity 131 (CAS 2618647-80-4)
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