N-(3,4-Dimethoxyphenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide CAS 1574626-72-4
| CAS No. | 1574626-72-4 |
| Molecular Formula | C23H27N3O4 |
| Molecular Weight | 409.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(3,4-Dimethoxyphenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574626-72-4), a certified reference material (molecular formula C23H27N3O4, MW 409.48 g/mol) for analytical method development and quality control.
The molecular framework of N-(3,4-Dimethoxyphenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (C23H27N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3,4-Dimethoxyphenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27N3O4 |
| Molecular Weight | 409.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(3,4-Dimethoxyphenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775408-74-6)
- N-(2,4-Dimethoxyphenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775408-78-0)
- 2-{4-[5-(2,5-dimethoxyphenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine (CAS 1026077-65-5)
- 3-(3,4-Dimethoxyphenyl)-5-[1-(3-methoxybenzoyl)pyrrolidin-2-yl]-1,2,4-oxadiazole (CAS 1790341-16-0)
- n-[(2,4-dimethoxyphenyl)methyl]-3-iodo-1h-pyrazolo[4,3-c]pyridin-4-amine (CAS 2056025-15-9)
- 6-(3,4-Dimethoxyphenyl)-2-((3-oxobutan-2-yl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-78-5)
- 10-(3,4-Dimethoxyphenyl)-3-heptyl-7-methyl-1,3,8,12-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),7,9,11-tetraene (CAS 685108-52-5)
- 4-[2-(2,6-Dimethoxyphenyl)-7-methyl-1H-benzimidazol-5-yl]-N-methyl-1-piperidineethanamine (CAS 912970-67-3)
Recommended Standards
- 9-[3-(Dibenzofuran-2-yl)phenyl]-9H-carbazole (CAS 1338446-77-7)
- 4'-(Anthracen-9-yl)-2,2':6',2''-terpyridine (CAS 163087-28-3)
- (4-(1H-Pyrrol-1-yl)phenyl)(4-(6-phenylpyrimidin-4-yl)piperazin-1-yl)methanone (CAS 1334371-64-0)
- 2,6-Bis(carbazol-9-yl)pyridine (CAS 168127-49-9)
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