Avermectin Impurity 1 CAS 157483-78-8
| CAS No. | 157483-78-8 |
| Molecular Formula | C50H72O14 |
| Molecular Weight | 897.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Avermectin Impurity 1.
Avermectin Impurity 1 (CAS 157483-78-8) is a certified pharmaceutical impurity reference standard with the molecular formula C50H72O14 and a molecular weight of 897.10 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Avermectin Impurity 1 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 897.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Avermectin Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C50H72O14 |
| Molecular Weight | 897.10 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
Related Avermectin Standards
Recommended Standards
- Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhamnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) (CAS 848784-87-2)
- Hederacolchiside A1 (CAS 106577-39-3)
- Oleanolic acid 3-O-β-D-glucosyl-( 1→3)-α-L-ramnosyl(1→2)-α-L-arabinoside (CAS 103956-33-8)
- [Ile7] Angiotensin III (CAS 52498-25-6)
- Mivacurium chloride Impurity 63 (CAS CATO-C4X-137563)
- Alfacalcidol Impurity N1 (CAS 71726-02-8)
- Atorvastatin Impurity 106 (CAS 1316291-19-6)
- (4S,5S,6S)-4-amino-6-methyltetrahydro-2H-pyran-2,5-diol (CAS 746564-84-1)
- Carbonic acid, compd. with cyclohexanamine (1:x) (CAS 20227-92-3)
- 4-(2,3-Dihydro-1H-inden-5-yloxy)-2-(trifluoromethyl)phenylamine (CAS 946698-36-8)
- 3α-acetyloxylanosta-8,24-dien-21-oic acid (CAS 174391-64-1)
- 3-((Tert-butoxycarbonyl)amino)heptanoic acid (CAS 676348-90-6)
- (2,5-Dimethoxybenzyl)1,2,3,4-tetrahydronaphthalen-1-ylamine (CAS 356092-88-1)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com