Tranexamic Acid EP Impurity E HCl CAS 157605-44-2
| CAS No. | 157605-44-2 |
| Molecular Formula | C16H28N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tranexamic Acid EP Impurity E HCl (CAS 157605-44-2, C16H28N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tranexamic Acid EP Impurity E HCl (C16H28N2O3HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tranexamic Acid EP Impurity E HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H28N2O3 HCl |
| Molecular Weight | 332.87 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tranexamic Standards
- Tranexamic Acid Impurity 18 (CAS 10473-24-2)
- Tranexamic Acid EP Impurity B (CAS 1197-17-7)
- Tranexamic Acid (CAS 1197-18-8)
- Tranexamic Acid-13C2,15N (CAS 1292837-95-6)
- Tranexamic Impurity 17 (CAS 13064-83-0)
- Tranexamic Acid EP Impurity F (CAS 1599413-49-6)
- Tranexamic Impurity 16 (CAS 1642-81-5)
- Tranexamic Acid RC 7 (CAS 180046-62-2)
Recommended Standards
- Fulvestrant Impurity 11 (CAS 757-06-2)
- Cabazitaxel Impurity 39 (CAS CATO-C4X-111539)
- Biapenem impurity 12 (CAS CATO-C4X-227312)
- CAS 2132345-12-9 (CAS 2132345-12-9)
- 2-Morpholino-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid (CAS 1172951-03-9)
- 2,5-Dimethylfuran-d3 (CAS CATO-C3D-3497)
- rac-tert-butyl N-{3-[(2R,3R)-3-methylpiperidin-2-yl]propyl}carbamate (CAS 1969288-20-7)
- 6-Fluorobenzo[d][1,2,3]triazin-4(1H)-one (CAS 1008742-31-1)
- 1-Ethyl-5-(piperidine-1-sulfonyl)-1h-1,3-benzodiazole-2-thiol (CAS 744242-76-0)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com