Barloxavir impurity 83 CAS 157652-27-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.157652-27-2
Molecular FormulaC9H7BrF2O2
Molecular Weight265.05 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Barloxavir impurity 83 CAS 157652-27-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 265.05 g/mol gives Barloxavir impurity 83 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Barloxavir impurity 83 (CAS 157652-27-2), a pharmacopoeial impurity reference standard (molecular formula C9H7BrF2O2, MW 265.05 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Barloxavir impurity 83 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 265.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Barloxavir impurity 83 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H7BrF2O2
Molecular Weight265.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentF/Br-containing

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