3,4-Difluoro-2-methylbenzoic Acid CAS 157652-31-8

Purity 97%+In StockPharmaceutical Standards
CAS No.157652-31-8
Molecular FormulaC8H6F2O2
Molecular Weight172.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Difluoro-2-methylbenzoic Acid CAS 157652-31-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 172.13 g/mol gives 3,4-Difluoro-2-methylbenzoic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3,4-Difluoro-2-methylbenzoic Acid (CAS 157652-31-8), a certified reference material (molecular formula C8H6F2O2, MW 172.13 g/mol) for analytical method development and quality control.

The molecular framework of 3,4-Difluoro-2-methylbenzoic Acid (C8H6F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3,4-Difluoro-2-methylbenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H6F2O2
Molecular Weight172.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentF-containing

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