(3R,4R,5R)-3,4-Dihydroxy-3-methyl-5-((trityloxy)methyl)dihydrofuran-2(3H)-one CAS 157666-05-2
| CAS No. | 157666-05-2 |
| Molecular Formula | C25H24O5 |
| Molecular Weight | 404.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 404.46 g/mol gives (3R,4R,5R)-3,4-Dihydroxy-3-methyl-5-((trityloxy)methyl)dihydrofuran-2(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3R,4R,5R)-3,4-Dihydroxy-3-methyl-5-((trityloxy)methyl)dihydrofuran-2(3H)-one (CAS 157666-05-2), molecular formula C25H24O5 and molecular weight 404.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3R,4R,5R)-3,4-Dihydroxy-3-methyl-5-((trityloxy)methyl)dihydrofuran-2(3H)-one (C25H24O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H24O5 |
| Molecular Weight | 404.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
Recommended Standards
- (3AR,5R,6aR)-2-((benzyloxy)carbonyl)-5-((tert-butoxycarbonyl)amino)hexahydrocyclopenta[c]pyrrole-3a(1H)-carboxylic acid (CAS 1537880-03-7)
- Ficusin A (CAS 173429-83-9)
- 8-tert-Butyl-4-(4-methyl-3-nitrobenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-10-9)
- (S)-5-((1-(Naphthalen-2-ylamino)-1-oxo-3-phenylpropan-2-yl)amino)-5-oxopentanoic acid (CAS 17479-62-8)
- 1-(4-Methyl-1H-benzo[d]imidazol-2-yl)guanidine (CAS 199853-99-1)
- (E)-3-(Furan-2-yl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 132434-55-0)
- 2,4-Dibromo-6-(difluoromethyl)-3-fluoropyridine (CAS 1805282-77-2)
- N-(1-(2-amino-1-(pyridin-3-yl)ethyl)piperidin-4-yl)acetamide (CAS 1918449-48-5)
- 6-Bromo-7-fluoroquinoline (CAS 127827-52-5)
- 1-(tert-Butyl) 3-methyl 5-(2,4-difluorophenyl)-4-hydroxy-1H-pyrrole-1,3-dicarboxylate (CAS 2258638-52-5)
- 4-[5-(trifluoromethyl)-1H-pyrazol-1-yl]aniline hydrochloride (CAS 1803586-22-2)
- N-Ethyl-4-methyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 68729-57-7)
- Benzyl 2-methyl-1-oxa-5-azaspiro[2.4]heptane-5-carboxylate (CAS 351370-72-4)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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