8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine CAS 1578245-95-0
| CAS No. | 1578245-95-0 |
| Molecular Formula | C8H16ClN3S |
| Molecular Weight | 221.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine.
CATO supplies 8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine (CAS 1578245-95-0), a certified reference material (molecular formula C8H16ClN3S, MW 221.75 g/mol) for analytical method development and quality control.
The molecular framework of 8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine (C8H16ClN3S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H16ClN3S |
| Molecular Weight | 221.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 5-chloro-2-methylsulfanyl-pyrido[4,3-d]pyrimidine (CAS 1255099-52-5)
- (5-chloro-3-methyl-thieno[2,3-c]pyridin-2-yl)methanol (CAS 1268834-51-0)
- 7-chloro-2-(methylsulfanyl)pyrido[2,3-d]pyrimidine (CAS 352328-41-7)
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- 2-Chloro-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline (CAS 500549-14-4)
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Recommended Standards
- 2-amino-5-(4-chlorophenyl)-1,3,4-thiadiazole 28004-62-8 5-(4-Chlorophenyl)-1,3,4-thiadiazole-2-amine 5-(4-chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine 5-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine 5-(4-chlorophenyl)-1,3,4-thiadiazol-2-ylamine 5-(4-chlorophenyl)-[1,3,4]thiadiazol-2-ylamine (CAS 28004-62-8)
- 5-Chloro-2-thienylmagnesium bromide, 0.25M 2-MeTHF (CAS 111762-30-2)
- 4-(4-Chlorobutyl)-2,2-dimethylthiomorpholine (CAS 1594498-38-0)
- (1R,5S,6r)-3-Benzyl-6-(chloromethyl)-3-azabicyclo[3.1.0]hexane (CAS 2102502-57-6)
- 4-Chloro-3,5-bis(trifluoromethyl)benzonitrile (CAS 62584-30-9)
- (3-Bromo-2-((4-fluorobenzyl)oxy)phenyl)boronic acid (CAS 849052-22-8)
- Methyl 2-ethyl-6-hydroxy-2,3-dihydrobenzofuran-2-carboxylate (CAS 653578-60-0)
- [1-(2-methylpropyl)cyclobutyl]methanamine (CAS 1015846-36-2)
- 7-Bromo-3-(methylthio)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 114260-89-8)
- 2-(4-Cyclohexylthiazol-2-yl)acetic acid (CAS 898382-22-4)
- 1-(Triphenylphosphoranylidene)pentan-2-one (CAS 17615-01-9)
- 1-(4-Fluoronaphthalen-1-yl)ethan-1-ol (CAS 1800-67-5)
- 3-Bromo-2-ethyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 918422-47-6)
- Peptide 433 (CAS CATO-CPTD788433)
Why CATO?
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