3-Chloro-1-methylisoquinoline CAS 15787-12-9
| CAS No. | 15787-12-9 |
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 177.63 g/mol gives 3-Chloro-1-methylisoquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-1-methylisoquinoline (CAS 15787-12-9), a certified reference material (molecular formula C10H8ClN, MW 177.63 g/mol) for analytical method development and quality control.
3-Chloro-1-methylisoquinoline (C10H8ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-1-methylisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-methylquinoline (CAS 10222-49-8)
- 8-Chloro-7-methylquinoline (CAS 102653-25-8)
- 5-Chloro-2-methoxynicotinaldehyde (CAS 103058-88-4)
- 3-Chloro-7-methylisoquinoline (CAS 1033201-77-2)
- 6-chloro-4-methoxy-pyridine-2-carbaldehyde (CAS 1060805-05-1)
- 4-chloro-3-methyl-isoxazolo[4,5-d]pyridazine (CAS 106584-75-2)
- 7-chloro-3-methyl-isoxazolo[4,5-d]pyridazine (CAS 106584-76-3)
- 2-Chloro-N-(oxan-4-yl)acetamide (CAS 1154931-91-5)
Recommended Standards
- 8-Chloro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine (CAS 156840-59-4)
- Rel-(2S,6R)-2,6-dimethylmorpholine-4-carbonyl chloride (CAS 1601099-54-0)
- 5-(Chloromethyl)-3-propyloxazolidin-2-one (CAS 156093-26-4)
- 2-Amino-1-chloronaphthalene (CAS 16452-11-2)
- 2-(4-Chlorophenyl)-2-methylmorpholine hydrochloride (CAS 109461-19-0)
- 24936-41-2 Benzene, 1-ethenyl-4-methyl-, homopolymer 1-Ethenyl-4-methylbenzene homopolymer (CAS 24936-41-2)
- (3-(Ethyl(methyl)carbamoyl)-2-fluorophenyl)boronic acid (CAS 2096337-94-7)
- N-(4-Isopropylbenzo[d]thiazol-2-yl)-3-methylisoxazole-5-carboxamide (CAS 946287-51-0)
- Orlistat Dimer Impurity (CAS 881900-54-5)
- 6-Chloro-3-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1097132-54-1)
- N-(1-((3R,5R,7R)-Adamantan-1-yl)ethyl)acetamide (CAS 180271-41-4)
- 1-(tert-Butyl) 3-ethyl 1H-pyrazole-1,3-dicarboxylate (CAS 870532-76-6)
- N-[(3,4-Dimethylphenyl)methyl]guanidine (CAS 1517094-26-6)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com