4-(Trifluoromethyl)nicotinamide CAS 158062-71-6
| CAS No. | 158062-71-6 |
| Molecular Formula | C7H5F3N2O |
| Molecular Weight | 190.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Trifluoromethyl)nicotinamide (CAS 158062-71-6), molecular formula C7H5F3N2O and molecular weight 190.12 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Trifluoromethyl)nicotinamide (C7H5F3N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-(Trifluoromethyl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F3N2O |
| Molecular Weight | 190.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- Trifluoromethyl benzoate (CAS 1035797-66-0)
- 1-(6-(Trifluoromethyl)pyrazin-2-yl)ethan-1-one (CAS 1197233-19-4)
- 2-Methyl-4-trifluoromethyl-pyrimidine-5-carbaldehyde (CAS 1260783-89-8)
- 3-(Trifluoromethyl)picolinaldehyde oxime (CAS 1280538-35-3)
- 4-Methyl-2-(trifluoromethyl)pyrimidine-5-carbaldehyde (CAS 1368083-12-8)
- 3-(Trifluoromethyl)isonicotinamide (CAS 1416713-20-6)
- 1-(4-(Trifluoromethyl)pyrimidin-5-yl)ethan-1-one (CAS 164341-77-9)
- 2-(Trifluoromethyl)isonicotinamide (CAS 1823892-98-3)
Recommended Standards
- 2-(Trifluoromethyl)benzoic Acid (CAS 433-97-6)
- 3-(Trifluoromethyl)benzoic Acid (CAS 454-92-2)
- Phenyl Trifluoroacetate (CAS 500-73-2)
- L-Tyrosine-13C9 (CAS 55443-60-2)
- 5-(5-Fluoro-2-hydroxybenzoyl)-2-oxo-1-(1,3-thiazol-2-yl)-1,2-dihydropyridine-3-carbonitrile (CAS 743444-72-6)
- 4-(2,5-Dimethoxyphenyl)butan-1-ol (CAS 1082496-27-2)
- 7-Allyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-imine hydrobromide (CAS 1949816-70-9)
- 1-Methylpiperidine-3-carbohydrazide (CAS 60779-77-3)
- 1-Ethyl-2-iodo-4-nitrobenzene (CAS 89976-46-5)
- 2-Bromo-6-chloro-4-fluorophenacyl chloride (CAS 1804382-56-6)
- 3-{4-[(E)-2-Chloro-but-2-en-(E)-ylidene]-5-methyl-ene-4,5-dihydro-1H-imidazol-2-yl}-propionic acid (CAS 878431-45-9)
- N-{4-[(difluoromethyl)sulfanyl]phenyl}-1,3-benzothiazol-2-amine (CAS 380349-37-1)
- 6-Bromo-7-methylisatin (CAS 129833-54-1)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com