1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aS)- CAS 1581274-41-0
| CAS No. | 1581274-41-0 |
| Molecular Formula | C12H11ClN2O2 |
| Molecular Weight | 250.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aS)- is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aS)- (CAS 1581274-41-0), molecular formula C12H11ClN2O2 and molecular weight 250.68 g/mol, is a CATO reference standard with documented purity and traceability.
1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aS)- (C12H11ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aS)- under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O2 |
| Molecular Weight | 250.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related H Standards
- 1H-Pyrrolo[2,1-c][1,4]benzodiazepine-3,11(2H,11aH)-dione, 7-chloro-5,10-dihydro-, (11aR)- (CAS 1581274-42-1)
- Pyrrolo[1,2-b]pyridazine-5,6,7-tricarboxylic acid (CAS 120266-84-4)
- 5-((1H-Pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-chlorothiazole (CAS 478258-75-2)
- 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID, 5-BROMO- 5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 5-BROMO-1H-PYRROLO[5,4-B]PYRIDINE-3-CARBOXYLIC ACID 5-BROMO-7-AZAINDOLE-3-CARBOXYLIC ACID 849068-61-7 ABBYPHARMA AP-14-10708 BC003965 (CAS 849068-61-7)
- 4-{pyrrolo[1,2-a]quinoxalin-4-yl}morpholine (CAS 478032-21-2)
- 1-(Pyrrolo[1,2-d][1,2,4]triazin-1-yl)piperidine-4-carboxylic acid (CAS 1708428-39-0)
- 1-(Pyrrolo[1,2-d][1,2,4]triazin-1-yl)piperidine-3-carboxylic acid (CAS 1713463-15-0)
- 2-{1H-pyrrolo[2,3-b]pyridine-3-sulfonamido}acetic acid (CAS 1193387-93-7)
Recommended Standards
- 945298-51-1 2-Chloro-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]acetamide MFCD09455289 (CAS 945298-51-1)
- 330978-46-6 2-Chloro-N-(5-methyl-isoxazol-3-yl)-2-phenyl-acetamide MFCD00435994 (CAS 330978-46-6)
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- 6-Fluoro-6-methyl-1,4-oxazepane hydrochloride (CAS 1823319-59-0)
- Tert-butyl 3-oxo-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxylate (CAS 1354951-38-4)
- O316O1ZGEG 139403-31-9 Pimilprost [INN] SM 10902 Acetic acid, (2-(octahydro-5-hydroxy-4-(3-hydroxy-5-methyl-1-nonenyl)-2-pentalenyl)ethoxy)-, methyl ester, (2R-(2-alpha,3a-alpha,4-alpha(1E,3S*,5S*),5-beta,6a-alpha))- (+)-Methyl (2-((2R,3aS,4R,5R,6aS)-octahydro-5-hydroxy-4-((1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl)-2-pentalenyl)ethoxy)acetate Pimilprost UNII-O316O1ZGEG (CAS 139403-31-9)
- 1-(4-bromophenyl)-4-(hydroxymethyl)pyrrolidin-2-one (CAS 133749-56-1)
- Ethyl 3-Oxo-3-(2-thienyl)propanoate (CAS 13669-10-8)
- N,N’-(3-Chloro-4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide) (CAS 143334-89-8)
- 6-(Pyrrolidine-1-sulfonyl)-1,2,3,4-tetrahydroquinoline (CAS 873208-54-9)
- 2-(2-Anthracen-9-yl-ethyl)-6-hydroxy-benzoic acid methyl ester (CAS 1171924-98-3)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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