(2R,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol CAS 1583260-14-3
| CAS No. | 1583260-14-3 |
| Molecular Formula | C24H46BrNO5Si |
| Molecular Weight | 536.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2R,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol.
(2R,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol (CAS 1583260-14-3) is a high-purity analytical reference standard with the molecular formula C24H46BrNO5Si and a molecular weight of 536.62 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, (2R,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 536.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H46BrNO5Si |
| Molecular Weight | 536.62 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-2-(5-bromo-3-pyridyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxy-tetrahydrofuran-2-ol (CAS 1583260-13-2)
- (R)-5-Amino-2-(((benzyloxy)carbonyl)(diphenyl(p-tolyl)methyl)amino)-5-oxopentanoic acid (CAS 200716-85-4)
- (S)-2-(((Benzyloxy)carbonyl)amino)-5-((diphenyl(p-tolyl)methyl)amino)-5-oxopentanoic acid (CAS 144317-19-1)
- (S)-4-((3,6-bis(3,5-dimethoxyphenyl)-9H-carbazol-9-yl)methyl)-2-methyl-4,5-dihydrooxazole (CAS 2357080-06-7)
- 2-(Di-tert-butylphosphino)-N,N,N-trimethylethanaminium chloride (CAS 360577-23-7)
- 4-bromo-5-fluoro-6-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 2765271-71-2)
- 9-Anthryldiazomethane (CAS 10401-59-9)
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- 4',4''',4''''',4'''''''-(Ethene-1,1,2,2-tetrayl)tetrakis(([1,1'-biphenyl]-3,5-dicarboxylic acid)) (CAS 1420471-57-3)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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