(4R,5R)-5-(benzyloxymethyl)-3,3-difluoro-4-hydroxy-tetrahydrofuran-2-one CAS 1583260-40-5
| CAS No. | 1583260-40-5 |
| Molecular Formula | C12H18F2O4 |
| Molecular Weight | 264.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 264.27 g/mol gives (4R,5R)-5-(benzyloxymethyl)-3,3-difluoro-4-hydroxy-tetrahydrofuran-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4R,5R)-5-(benzyloxymethyl)-3,3-difluoro-4-hydroxy-tetrahydrofuran-2-one (CAS 1583260-40-5), molecular formula C12H18F2O4 and molecular weight 264.27 g/mol, is a CATO reference standard with documented purity and traceability.
(4R,5R)-5-(benzyloxymethyl)-3,3-difluoro-4-hydroxy-tetrahydrofuran-2-one (C12H18F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18F2O4 |
| Molecular Weight | 264.27 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Recommended Standards
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- 4-{3-[(2-methylprop-2-enoyl)oxy]propoxy}benzoic acid (CAS 140918-56-5)
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- 3-Isopropyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine (CAS 376587-12-1)
- 1-(5-(Benzyloxy)-2,4-dichlorophenyl)-2-(methylthio)-1H-imidazole (CAS 338967-14-9)
- 2-(Hydroxymethylene)benzofuran-3(2H)-one (CAS 389579-63-9)
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- (2-Methoxy-4-nitrophenyl)(methyl)sulfane (CAS 4163-77-3)
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- 6-(Furan-3-yl)-2-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 100244-31-3)
- (E)-1-(4-Benzylpiperazino)-4,4,5,5,5-pentafluoro-1-penten-3-one (CAS 866144-14-1)
- Cyclopeptide-5 (CAS 197172-76-2)
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