(3S,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-3-methyl-tetrahydrofuran-2-one CAS 1583260-50-7
| CAS No. | 1583260-50-7 |
| Molecular Formula | C19H35FO4Si |
| Molecular Weight | 374.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (3S,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-3-methyl-tetrahydrofuran-2-one (C19H35FO4Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(3S,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-3-methyl-tetrahydrofuran-2-one (CAS 1583260-50-7), molecular formula C19H35FO4Si and molecular weight 374.56 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (3S,4R,5R)-5-(benzyloxymethyl)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-3-methyl-tetrahydrofuran-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H35FO4Si |
| Molecular Weight | 374.56 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Recommended Standards
- (+)-2,2′-isopropylidenebis[(4<I>R</I>)-4-benzyl-2-oxazoline] (CAS 141362-77-8)
- 3-(1-Oxopropoxy)-pregnan-20-one (CAS 171494-53-4)
- 1,3-Bis(1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)propane-1,3-dione (CAS 1212369-68-0)
- 2',4'-difluoro-3-(2-methylphenyl)propiophenone (CAS 898790-08-4)
- 3-Chloro-2,4-dimethylbenzoic acid (CAS 1632385-49-9)
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- tert-Butyl (S)-(8-azaspiro[4.5]decan-1-yl)carbamate (CAS 2374137-12-7)
- 2-Methyl-3-(4-methoxyphenyl)propanal (CAS 5462-06-6)
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Why CATO?
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