Timolol EP Impurity H CAS 158636-97-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.158636-97-6
Molecular FormulaC13H24N4O3S
Molecular Weight316.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Timolol EP Impurity H CAS 158636-97-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 316.42 g/mol gives Timolol EP Impurity H distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Timolol EP Impurity H (CAS 158636-97-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H24N4O3S and a molecular weight of 316.42 g/mol.

Based on its molecular formula C13H24N4O3S, Timolol EP Impurity H contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H24N4O3S
Molecular Weight316.42 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Nitrogen Atoms4
Sulfur Atoms1

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