4-(Phenylamino)nicotinic acid CAS 15871-49-5
| CAS No. | 15871-49-5 |
| Molecular Formula | C12H10N2O2 |
| Molecular Weight | 214.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Phenylamino)nicotinic acid (CAS 15871-49-5), molecular formula C12H10N2O2 and molecular weight 214.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Phenylamino)nicotinic acid (C12H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Phenylamino)nicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O2 |
| Molecular Weight | 214.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Phenylamino Standards
- 6-(Phenylamino)pyridine-3-carboxylic acid (CAS 13426-16-9)
- 2-(6-(Phenylamino)pyridin-3-yl)ethanol (CAS 1355219-77-0)
- 2-(Phenylamino)-2-(thiophen-2-yl)acetonitrile (CAS 81994-43-6)
- 2-(Phenylamino)-2-(thiophen-3-yl)acetonitrile (CAS 904817-00-1)
- 2-phenyl-2-(phenylamino)ethan-1-ol (CAS 13891-02-6)
- 1-Phenyl-2-(phenylamino)ethan-1-ol (CAS 31121-09-2)
- 6-(phenylamino)pyrimidine-4-carboxylic acid (CAS 1208980-40-8)
- 2-(Phenylamino)pyrimidine-4-carboxylic acid (CAS 1360802-78-3)
Recommended Standards
- 2-(3-Ethoxy-4-hydroxybenzylidene)malononitrile (CAS 15728-34-4)
- 1,2-dimethyl (1R,2R)-4-oxocyclohexane-1,2-dicarboxylate (CAS 159910-01-7)
- 5-Ethoxy-2-phenyloxazole-4-carbonitrile (CAS 156210-50-3)
- 3-Methoxy-5,7-dihydropyrrolo[1,2-a]quinoxalin-6(1H)-one (CAS 160657-07-8)
- Nordihydrocodeine (CAS 845-69-2)
- Tert-butyl 5-(hydroxymethyl)bicyclo[3.1.1]Heptane-1-carboxylate (CAS 122699-63-2)
- (2S,3S)-2,3-Dihydroxy-3-(phenylcarbamoyl)-propanoic acid (CAS 206761-64-0)
- methyl 4-(3-iodopyridin-4-yl)piperazine-1-carboxylate (CAS 1803566-55-3)
- methyl (1S,3R)-3-aminocyclohexanecarboxylate;hydrochloride (CAS 222530-35-0)
- 2-Bromo-6-iodo-4-(trifluoromethyl)aniline (CAS 875306-20-0)
- 4-Chloro-N-(5-iodopyridin-2-yl)butanamide (CAS 338748-92-8)
- 1-Bromo-4-methoxyimidazo[1,2-a]quinoxaline (CAS 344776-90-5)
- 4-Cyclopropylmethanesulfonylbenzoic acid (CAS 1154385-37-1)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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