4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) CAS 159308-03-9

Purity 97%+In StockPharmaceutical Standards
CAS No.159308-03-9
Molecular FormulaC22H22N2O6
Molecular Weight410.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) CAS 159308-03-9 chemical structure

Description

The occurrence of 4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) (CAS 159308-03-9) is a high-purity analytical reference standard with the molecular formula C22H22N2O6 and a molecular weight of 410.42 g/mol.

4,6-Dimethoxy-b-methyl-3-phenoxy Ambrisentan (Mixture of Diastereomers) (C22H22N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H22N2O6
Molecular Weight410.42 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Nitrogen Atoms2

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