2-Chloro-1,8-naphthyridine CAS 15936-10-4
| CAS No. | 15936-10-4 |
| Molecular Formula | C8H5ClN2 |
| Molecular Weight | 164.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-1,8-naphthyridine (CAS 15936-10-4), molecular formula C8H5ClN2 and molecular weight 164.59 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-1,8-naphthyridine (C8H5ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 164.59 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2 |
| Molecular Weight | 164.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- 3-Chloro-1,5-naphthyridine (CAS 1309379-14-3)
Recommended Standards
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- 4-Chloro-1,7-naphthyridine (CAS 16287-97-1)
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- tert-Butyl 4-(3-(4-bromophenyl)propanoyl)piperazine-1-carboxylate (CAS 1704065-10-0)
- 3-Bromo-5-chlorophenacyl bromide (CAS 1261522-20-6)
- n-(3,5-Difluorophenethyl)butan-2-amine (CAS 1249475-04-4)
- (2-Amino-5-(methylsulfonyl)phenyl)dimethylphosphine oxide (CAS 2903924-11-6)
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