Bis(4-chlorophenyl)phosphine oxide CAS 15948-60-4
| CAS No. | 15948-60-4 |
| Molecular Formula | C12H9Cl2OP |
| Molecular Weight | 271.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to organophosphorus functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Bis(4-chlorophenyl)phosphine oxide is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 271.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Bis(4-chlorophenyl)phosphine oxide (CAS 15948-60-4) is a high-purity analytical reference standard with the molecular formula C12H9Cl2OP and a molecular weight of 271.08 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9Cl2OP |
| Molecular Weight | 271.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
Related Bis Standards
- 4-Chlorophenyl Sulfoxide (CAS 3085-42-5)
- 2-(4-Chlorophenyl)-2-morpholinoethanethioamide (CAS 951902-97-9)
- 2-(4-Chlorophenyl)-2-(phenethylamino)acetonitrile (CAS 1018527-41-7)
- 1-(2-Chlorophenyl)-3-(2-ethyl-2-hydroxybutyl)urea (CAS 1252350-58-5)
- 1-[(4-chlorophenyl)methyl]-5,6-dimethyl-1h-1,3-benzodiazole (CAS 141472-79-9)
- 4-((4-Chlorophenyl)thio)thiophene-3-carboxylic acid (CAS 149609-86-9)
- 2-(2-Chlorophenyl)-2-(1h-indol-3-yl)ethan-1-amine (CAS 735322-70-0)
- (2E)-3-(3-Chlorophenyl)-1-(4-ethylphenyl)prop-2-en-1-one (CAS 1176509-18-4)
Recommended Standards
- 4-Bromo-1-isobutyl-3-trifluoromethyl-1H-pyrazole (CAS 1437794-62-1)
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- 4-Bromo-1-butyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1437794-58-5)
- (4-((2-Methoxyphenyl)carbamoyl)phenyl)boronic acid (CAS 1704069-56-6)
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- 2-(6-Chloropyridin-3-yl)-2-(dimethylamino)acetic acid (CAS 1007878-77-4)
- 2-Amino-4-bromo-6-(trifluoromethyl)benzonitrile (CAS 1805022-91-6)
- 4'-fluoro-1',2'-dihydrospiro[cyclopentane-1,3'-indole] (CAS 1235439-61-8)
- 4-Methyl-N-(2-methyl-1-phenylpropan-2-yl)benzenesulfonamide (CAS 110871-36-8)
- Carbazomycin A (CAS 75139-39-8)
- 2-Chloro-6-(phenylthio)pyrimidin-4(1H)-one (CAS 284682-02-6)
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