2-Amino-5-fluoro-6-methylpyrimidin-4(3H)-one CAS 1597-35-9

Description

The occurrence of 2-Amino-5-fluoro-6-methylpyrimidin-4(3H)-one is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Amino-5-fluoro-6-methylpyrimidin-4(3H)-one (CAS 1597-35-9), molecular formula C5H6FN3O and molecular weight 143.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Amino-5-fluoro-6-methylpyrimidin-4(3H)-one (C5H6FN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Amino-5-fluoro-6-methylpyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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