5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine CAS 1600342-90-2
| CAS No. | 1600342-90-2 |
| Molecular Formula | C7H8BrFN2 |
| Molecular Weight | 219.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine.
5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine (CAS 1600342-90-2), molecular formula C7H8BrFN2 and molecular weight 219.05 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine (C7H8BrFN2) contains a nitrile group, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 219.05 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8BrFN2 |
| Molecular Weight | 219.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- (2-Bromo-5-fluorobenzyl)hydrazine (CAS 1016529-00-2)
- (5-Bromo-2-fluorobenzyl)hydrazine (CAS 1016699-41-4)
- (1s)-1-(4-Bromo-2-fluorophenyl)ethan-1-ol (CAS 1026088-11-8)
- 1-Bromo-4-ethoxy-2-fluorobenzene (CAS 107713-66-6)
- (R)-2-Bromo-1-(4-fluorophenyl)ethanol (CAS 1097211-38-5)
- 4-bromo-1-ethoxy-2-fluorobenzene (CAS 115467-08-8)
- (S)-2-Bromo-1-(3-fluorophenyl)ethan-1-ol (CAS 1176484-68-6)
- 5-Bromo-2-fluoro-3-methylbenzyl alcohol (CAS 1197944-22-1)
Recommended Standards
- 1-(2-Bromo-3-fluorophenyl)ethanol (CAS 1593042-45-5)
- 1-Bromo-2-fluoro-4-(methoxymethyl)benzene (CAS 162744-47-0)
- (S)-1-(5-Bromo-2-fluorophenyl)ethan-1-ol (CAS 1568209-71-1)
- (1s)-1-(2-Bromo-5-fluorophenyl)ethan-1-ol (CAS 1689852-87-6)
- 3(or 5)-[[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-1-naphthalenyl]azo]-2-hydroxy-Benzoic acid,disodium salt (CAS 34977-63-4)
- (2-Oxo-3-(4-sulfamoylphenyl)oxazolidin-5-yl)methyl acetate (CAS 87472-22-8)
- N-allyl-7,9-dimethyl-2-((4-methylbenzyl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-amine (CAS 672950-71-9)
- 1-(3-Bromo-2-hydroxypropyl)-6-chloroquinolin-1-ium bromide (CAS 7512-75-6)
- 2-Bromo-5-fluoro-3-methylpyridine (CAS 38186-85-5)
- 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isothiazole (CAS 1310419-07-8)
- Dopamine Impurity 64 (CAS CATO-C4X-190864)
- CAS 27064-04-6 (CAS 27064-04-6)
- 6-Fluoro-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one (CAS 1364719-75-4)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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