tert-Butyl (3S)-3-(aminomethyl)-3-fluoropyrrolidine-1-carboxylate CAS 1601461-44-2
| CAS No. | 1601461-44-2 |
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl (3S)-3-(aminomethyl)-3-fluoropyrrolidine-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
tert-Butyl (3S)-3-(aminomethyl)-3-fluoropyrrolidine-1-carboxylate (CAS 1601461-44-2) is a high-purity analytical reference standard with the molecular formula C10H19FN2O2 and a molecular weight of 218.27 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl (3R)-3-(aminomethyl)-3-fluoropyrrolidine-1-carboxylate (CAS 1601461-43-1)
- tert-Butyl (2R,4S)-2-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 1627972-84-2)
- tert-Butyl N-[(3S,5S)-5-fluoropiperidin-3-yl]carbamate (CAS 1593969-81-3)
- tert-Butyl ((3R,4S)-3-fluoropiperidin-4-yl)carbamate (CAS 1630815-57-4)
- (R)-2-(3-Methylbenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1217840-70-4)
- (1R,3R)-3-amino-N,1-dimethylcyclopentane-1-carboxamide (CAS 2306254-63-5)
- Ethyl 6-methyl-3-nitro-2-oxo-1,2-dihydropyridine-4-carboxylate (CAS 70026-89-0)
- 2-(1-oxo-1H-isochromen-3-yl)acetic acid (CAS 39153-95-2)
- 5-(bromomethyl)-3-methoxy-1,2-thiazole (CAS 1909337-30-9)
- 5-aminotetrahydro-2H-pyran-3-carbonitrile (CAS 2091702-11-1)
- 2-{4-[(3-Amino-4-chlorophenyl)sulfonyl]-1-piperazinyl}-1-ethanol (CAS 1154310-95-8)
- 2-(Benzo[d]thiazol-2-yl)-3-((2-ethoxyphenyl)amino)acrylonitrile (CAS 637748-82-4)
- Allyl 2-amino-4-methylthiazole-5-carboxylate (CAS 247242-56-4)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com