1-[(3,4-difluorophenyl)methyl]piperidin-4-amine CAS 160358-08-7
| CAS No. | 160358-08-7 |
| Molecular Formula | C12H16F2N2 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(3,4-difluorophenyl)methyl]piperidin-4-amine (C12H16F2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-[(3,4-difluorophenyl)methyl]piperidin-4-amine (CAS 160358-08-7) is a high-purity analytical reference standard with the molecular formula C12H16F2N2 and a molecular weight of 226.27 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16F2N2 |
| Molecular Weight | 226.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluorophenyl Standards
- 2-(2,5-Difluorophenyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 1096880-44-2)
- 1-[(2,3-Difluorophenyl)methyl]-1,4-diazepane (CAS 1153434-52-6)
- 1-[(3,4-Difluorophenyl)methyl]-1,4-diazepane (CAS 1178292-54-0)
- 1-[(2,6-Difluorophenyl)methyl]-1,4-diazepane (CAS 1179515-18-4)
- 1-[(2,5-Difluorophenyl)methyl]-1,4-diazepane (CAS 1183376-34-2)
- 1-[(2,4-Difluorophenyl)methyl]-1,4-diazepane (CAS 1183888-56-3)
- 1-[(3,5-Difluorophenyl)methyl]-1,4-diazepane (CAS 1240566-10-2)
- 1-[(2,4-Difluorophenyl)methyl]-2-methylpiperazine (CAS 1240566-64-6)
Recommended Standards
- tert-Butyl 3-cyano-5-methylmorpholine-4-carboxylate (CAS 1598179-95-3)
- 1-(3,5-Difluoro-benzyl)-piperidin-4-ylamine (CAS 160358-09-8)
- 1-(p-Tolyl)-6,7-dihydro-1H-indazol-4(5H)-one (CAS 15881-68-2)
- 2-(3-(Benzyloxy)phenyl)acetaldehyde (CAS 160721-23-3)
- 1-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-hydroxy-9H-purin-2-yl)propan-2-one (CAS 110851-53-1)
- 3-[(E)-[[(1R,2R)-2-[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]thioureido]cyclohexyl]imino]methyl]-5-(tert-butyl)-4-hydroxyphenyl pivalate (CAS 462632-54-8)
- 2-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)propan-1-amine (CAS 956821-83-3)
- 3-Chloro-5-(pentafluoro-λ6-sulfanyl)aniline (CAS 1240257-97-9)
- 2-(4-Benzylphenoxy)ethan-1-amine (CAS 138113-73-2)
- 2-oxo-6-(trifluoromethyl)piperidine-3-carboxylic acid (CAS 1031130-72-9)
- L-malic acid-1-<SUP>13</SUP>C (CAS 180991-05-3)
- Methyl (2S,4S)-4-[(5-chloro[1,1-biphenyl]-2-yl)-oxy]-2-pyrrolidinecarboxylate hydrochloride (CAS 1354486-26-2)
- N-Ethylpiperidine-4-amine dihydrochloride (CAS 1233953-08-6)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com