(R)-6-Fluorospiro[chromane-2,1'-cyclobutan]-4-ol CAS 1604253-26-0

Description

The occurrence of (R)-6-Fluorospiro[chromane-2,1'-cyclobutan]-4-ol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(R)-6-Fluorospiro[chromane-2,1'-cyclobutan]-4-ol (CAS 1604253-26-0) is a high-purity analytical reference standard with the molecular formula C12H13FO2 and a molecular weight of 208.23 g/mol.

The molecular framework of (R)-6-Fluorospiro[chromane-2,1'-cyclobutan]-4-ol (C12H13FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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