Diphenyl(trifluoromethyl)phosphane CAS 1605-56-7
| CAS No. | 1605-56-7 |
| Molecular Formula | C13H10F3P |
| Molecular Weight | 254.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Diphenyl(trifluoromethyl)phosphane (CAS 1605-56-7) is a high-purity analytical reference standard with the molecular formula C13H10F3P and a molecular weight of 254.19 g/mol.
The molecular framework of Diphenyl(trifluoromethyl)phosphane (C13H10F3P) is characterized by organophosphorus functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10F3P |
| Molecular Weight | 254.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
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Recommended Standards
- 2-Acetamido-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1216134-71-2)
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- 3-Methyl-5-(2,2,2-trifluoroacetamido)isothiazole-4-carboxylic acid (CAS 1179953-18-4)
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- 2-(3-Methyl-2-thioxo-2,3-dihydro-1H-imidazol-4-yl)acetic acid (CAS 1091908-73-4)
- 2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethan-1-one (CAS 957003-43-9)
- (2-Phenylethyl)(propan-2-yl)amine (CAS 52007-97-3)
- 4-methylenepiperidine (CAS 148133-82-8)
- (S)-4-Fluoro-2-(2-hydroxypropyl)benzonitrile (CAS 1392814-62-8)
- 4-(4-Methylphenoxy)-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine (CAS 339018-74-5)
- 2-Isobutyl-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 67562-23-6)
- 5-Chloro-7-((dimethylamino)methyl)quinolin-8-ol (CAS 100119-17-3)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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