2-((3-(Trifluoromethyl)phenyl)carbamoyl)benzoic acid CAS 16053-36-4
| CAS No. | 16053-36-4 |
| Molecular Formula | C15H10F3NO3 |
| Molecular Weight | 309.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-((3-(Trifluoromethyl)phenyl)carbamoyl)benzoic acid (CAS 16053-36-4), a certified reference material (molecular formula C15H10F3NO3, MW 309.24 g/mol) for analytical method development and quality control.
The molecular framework of 2-((3-(Trifluoromethyl)phenyl)carbamoyl)benzoic acid (C15H10F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10F3NO3 |
| Molecular Weight | 309.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 2-(3-(Trifluoromethyl)phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione (CAS 433264-21-2)
- 2-[2-(Trifluoromethyl)benzamido]benzoic acid (CAS 866150-35-8)
- N-(2-(trifluoromethyl)phenyl)benzo[d][1,3]dioxole-5-carboxamide (CAS 349415-11-8)
- 6-((2-(Trifluoromethyl)benzyl)oxy)-1H-purin-2-amine (CAS 168098-98-4)
- 2-((2-Oxo-2-((3-(trifluoromethyl)phenyl)amino)ethyl)sulfinyl)acetic acid (CAS 338953-86-9)
- 2-({2-Oxo-2-[4-(trifluoromethyl)anilino]ethyl}sulfinyl)acetic acid (CAS 344267-47-6)
- 1-{[3,5-Bis(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-amine (CAS 1240566-22-6)
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Recommended Standards
- 1-(Adamantan-1-ylmethyl)-4-bromo-5-methyl-1H-pyrazole (CAS 1430845-69-4)
- (E)-[1-(Pyrazin-2-yl)ethylidene]amino 4-(trifluoromethyl)benzoate (CAS 866149-23-7)
- 2-(4-Methylpiperazin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1390682-08-2)
- (Z)-[1-(Pyrazin-2-yl)ethylidene]amino 3-(trifluoromethyl)benzoate (CAS 866019-14-9)
- 4-Phenyltetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 873383-88-1)
- 5-Cyano-2-(trifluoromethyl)nicotinic acid (CAS 1211537-37-9)
- 2-Bromo-2’-hydroxyacetophenone Oxime (CAS 887353-75-5)
- 2,5-Difluoro-N-(3-methylbutan-2-yl)aniline (CAS 1019635-26-7)
- (R)-2-Amino-5-(4-chlorophenyl)pentanoic acid (CAS 220283-76-1)
- Warfarin impurity 13 (CAS CATO-C4X-17813)
- (R)-tert-Butyl 4-(2-oxo-2-(2-oxo-4-phenyloxazolidin-3-yl)ethyl)piperidine-1-carboxylate (CAS 1159845-42-7)
- 6-bromo-2-cyclopropyl-3-methylquinoline-4-carboxylic acid (CAS 1376013-52-3)
- 2-(2-(2-Nitrophenyl)hydrazine-1-carbonyl)benzoic acid (CAS 32669-19-5)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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