6-Methyl-2H-pyrido[1,2-a]pyrimidin-2-one CAS 16075-68-6

Purity 97%+In StockPharmaceutical Standards
CAS No.16075-68-6
Molecular FormulaC9H8N2O
Molecular Weight160.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Methyl-2H-pyrido[1,2-a]pyrimidin-2-one CAS 16075-68-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

6-Methyl-2H-pyrido[1,2-a]pyrimidin-2-one (CAS 16075-68-6), molecular formula C9H8N2O and molecular weight 160.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-Methyl-2H-pyrido[1,2-a]pyrimidin-2-one (C9H8N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H8N2O
Molecular Weight160.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms2

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