2’’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel CAS 160768-75-2

Purity 97%+In StockPharmaceutical Standards
CAS No.160768-75-2
Molecular FormulaC50H73NO12Si2
Molecular Weight936.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2’’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel CAS 160768-75-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 936.29 g/mol gives 2’’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2’’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel (CAS 160768-75-2), a certified reference material (molecular formula C50H73NO12Si2, MW 936.29 g/mol) for analytical method development and quality control.

The molecular framework of 2’’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel (C50H73NO12Si2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC50H73NO12Si2
Molecular Weight936.29 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Nitrogen Atoms1

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