2-(2,2-Difluoroacetamido)acetic acid CAS 160845-43-2
| CAS No. | 160845-43-2 |
| Molecular Formula | C4H5F2NO3 |
| Molecular Weight | 153.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 153.08 g/mol gives 2-(2,2-Difluoroacetamido)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(2,2-Difluoroacetamido)acetic acid (CAS 160845-43-2), a certified reference material (molecular formula C4H5F2NO3, MW 153.08 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2,2-Difluoroacetamido)acetic acid (C4H5F2NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,2-Difluoroacetamido)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H5F2NO3 |
| Molecular Weight | 153.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroacetamido Standards
Recommended Standards
- [(2,2-difluoroethyl)carbamoyl]formic acid (CAS 1461706-89-7)
- 1,1-Difluoro-1-Nitro-2-Butanone (CAS 33128-11-9)
- N-Acetylaminomethylphosphoric Acid (CAS 57637-97-5)
- 2,2,3,3-Tetrafluorocyclobutane-1-carbonitrile (CAS 356-81-0)
- 7,8-Dihydronaphthalen-1-yl trifluoromethanesulfonate (CAS 802918-37-2)
- 1-[3,5-Bis(trifluoromethyl)phenyl]cyclobutanamine (CAS 1314714-46-9)
- 5-Fluoro-4-iodo-2-methylaniline (CAS 307306-08-7)
- 2-Amino-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)acetamide (CAS 1247158-03-7)
- 1-Benzyl-2,5-dimethyl-1H-indole-3-carbaldehyde (CAS 1228552-95-1)
- 6-(2-Chlorophenyl)-6-oxohexanenitrile (CAS 898767-78-7)
- 3-Oxo-3-(2,4,5-trifluorophenyl)propanenitrile (CAS 142501-42-6)
- N-(5-fluoronaphthalen-1-yl)pyridin-4-amine (CAS CATO-C3D-262361)
- 5-Bromo-7-chloro-1H-benzo[d]imidazole (CAS 1360932-45-1)
- Exenatide (CAS 141758-74-9)
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