3-Amino-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid CAS 1609255-54-0
| CAS No. | 1609255-54-0 |
| Molecular Formula | C10H6F3NO2S |
| Molecular Weight | 261.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 1609255-54-0), molecular formula C10H6F3NO2S and molecular weight 261.22 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Amino-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (C10H6F3NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 261.22 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-5-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6F3NO2S |
| Molecular Weight | 261.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-4-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 1648807-88-8)
- 3-Amino-7-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 1648807-91-3)
- 3-Amino-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 2379918-55-3)
- 3-Amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 940773-46-6)
- 6-Amino-1-(1,3-benzodioxol-5-ylmethyl)-pyrimidine-2,4(1H,3H)-dione (CAS 157927-50-9)
- 6-Amino-1-(3-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (CAS 910443-02-6)
- 6-Amino-1-(4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (CAS 900463-65-2)
- 4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one (CAS 4298-10-6)
Recommended Standards
- (E)-3-(dimethylamino)-1-(3-fluoro-5-(trifluoromethyl)phenyl)prop-2-en-1-one (CAS 154258-42-1)
- 5-(3-(Trifluoromethoxy)phenyl)-1,3,4-thiadiazol-2-amine (CAS 1478301-79-9)
- 5-(2-(Trifluoromethoxy)phenyl)-1,3,4-thiadiazol-2-amine (CAS 1466417-52-6)
- Ethyl 2,2-difluoro-4,4-dihydroxy-4-pyridin-4-ylbutanoate (CAS 1706449-05-9)
- (S)-Methyl 2-(pyrrolidin-2-yl)acetate (CAS 53912-83-7)
- 1-(piperazin-1-yl)cyclopropane-1-carboxylic acid hydrochloride (CAS 1955506-45-2)
- 2-Furfurylthio-3-methylpyrazine (CAS 65530-53-2)
- Ethyl 2-(6-bromo-3-cyano-2-(trifluoromethyl)phenyl)acetate (CAS 1805585-99-2)
- (3',5'-Dichloro-[1,1'-biphenyl]-3-yl)methanol (CAS 208941-51-9)
- 4-[3-(Dibutylamino)propoxy]benzoic Acid-d6 Hydrochloride (CAS 1329808-49-2)
- Methyl (S)-3-amino-2-benzylpropanoate (CAS 776327-05-0)
- 1-(5-Methylthiophen-2-yl)hexane-1,3-dione (CAS 1250722-35-0)
- tert-Butyl (2-(6-acetyl-4-iodopyridin-2-yl)ethyl)carbamate (CAS 1393573-76-6)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com