Tert-butyl3-hydroxy-3-[2-(trifluoromethyl)phenyl]azetidine-1-carboxylate CAS 1609671-83-1
| CAS No. | 1609671-83-1 |
| Molecular Formula | C15H18F3NO3 |
| Molecular Weight | 317.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tert-butyl3-hydroxy-3-[2-(trifluoromethyl)phenyl]azetidine-1-carboxylate (C15H18F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Tert-butyl3-hydroxy-3-[2-(trifluoromethyl)phenyl]azetidine-1-carboxylate (CAS 1609671-83-1), a certified reference material (molecular formula C15H18F3NO3, MW 317.30 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tert-butyl3-hydroxy-3-[2-(trifluoromethyl)phenyl]azetidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18F3NO3 |
| Molecular Weight | 317.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl3-hydroxy-3-[3-(trifluoromethyl)phenyl]azetidine-1-carboxylate (CAS 1609671-73-9)
- (R)-1-((R)-1-(4-Methoxyphenyl)ethyl)-4-((S)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-2-one (CAS 1650544-92-5)
- tert-Butyl (3-acetyl-5-(trifluoromethyl)benzyl)carbamate (CAS 1393534-44-5)
- (R)-1-((R)-1-(4-Methoxyphenyl)ethyl)-4-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-2-one (CAS 1650544-94-7)
- 4-(tert-Butyl)-2-phenyloxazol-5(4H)-one (CAS 71953-55-4)
- 2-Allyl-7-amino-3,4-dihydroisoquinolin-1(2h)-one (CAS 1344331-94-7)
- 1-(4-Hydroxyphenyl)piperazine (CAS 56621-48-8)
- 5-((Methylthio)methyl)-3-oxo-2,3-dihydroisoxazole-4-carbonyl chloride (CAS 98406-62-3)
- N-(1-(1-(2-Methylallyl)-1H-benzo[d]imidazol-2-yl)ethyl)furan-2-carboxamide (CAS 919972-35-3)
- (3S)-3-Amino-N-cyclopropyl-2-hydroxypentanamide (CAS 910607-16-8)
- 2,3-Dichloro-1,4-bis(trifluoromethyl)benzene (CAS 887268-06-6)
- 3-(Pyridin-4-ylamino)isobenzofuran-1(3H)-one (CAS 75483-56-6)
- (2-{5-[(3,4-Dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}ethyl)methylamine hydrochloride (CAS 1332531-11-9)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com