16097-63-5 4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine 4-chloro-2-(methylthio)-6-(trifluoromethyl)pyrimidine CAS 16097-63-5
| CAS No. | 16097-63-5 |
| Molecular Formula | C6H4ClF3N2S |
| Molecular Weight | 228.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
16097-63-5 4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine 4-chloro-2-(methylthio)-6-(trifluoromethyl)pyrimidine (CAS 16097-63-5) is a high-purity analytical reference standard with the molecular formula C6H4ClF3N2S and a molecular weight of 228.62 g/mol.
The molecular framework of 16097-63-5 4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine 4-chloro-2-(methylthio)-6-(trifluoromethyl)pyrimidine (C6H4ClF3N2S) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 16097-63-5 4-Chloro-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine 4-chloro-2-(methylthio)-6-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF3N2S |
| Molecular Weight | 228.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-(trifluoromethylthio)pyridine-3-amine (CAS 1204234-98-9)
- 3-Chloro-5-((trifluoromethyl)thio)pyridin-2-amine (CAS 1383834-40-9)
- 1-Chloro-4-((trifluoromethyl)sulfinyl)benzene (CAS 708-66-7)
- 1-Chloro-4-(difluoromethoxy)naphthalene (CAS 743451-75-4)
- 2-Chloro-4-((trifluoromethyl)thio)phenol (CAS 70783-74-3)
- 2-Chloro-4-(methylthio)-5-(trifluoromethyl)pyrimidine (CAS 919116-35-1)
- 4-Chloro-2-(methylthio)-5-(trifluoromethyl)pyrimidine (CAS 919116-36-2)
- 5-Chloro-2-(methylthio)-4-(trifluoromethyl)pyrimidine (CAS 2089334-51-8)
Recommended Standards
- Methyl 7-chloro-8-fluoroimidazo[1,5-a]pyridine-3-carboxylate (CAS 2757927-25-4)
- Methyl 6-chloro-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 695202-42-7)
- Methyl 3-chloro-6-fluoro-1H-indazole-4-carboxylate (CAS 885521-77-7)
- Methyl 3-chloro-4-fluoro-2H-indazole-6-carboxylate (CAS 885521-38-0)
- N-(1,2,3,4-Tetrahydronaphthalen-1-yl)acetamide (CAS 42071-43-2)
- 1-(m-Tolyl)ethan-1-amine (CAS 70138-19-1)
- 4-methyl-4-(propan-2-yl)piperidine hydrochloride (CAS 1123-23-5)
- n-(6-Methoxybenzo[d]thiazol-2-yl)acetamide (CAS 100817-90-1)
- 2-(1,1-Dioxidodihydro-2H-thiopyran-3(4H)-ylidene)acetic acid (CAS 1344846-39-4)
- 2-(2,4-Difluorophenyl)-2-(dimethylamino)acetic acid (CAS 1218641-29-2)
- 2,3,5,6-Tetrafluoro-3'-(trifluoromethoxy)-[1,1'-biphenyl]-4-amine (CAS 867288-02-6)
- 2-Bromo-N-2-naphthylbutanamide (CAS 1282180-24-8)
- 2-Chloro-N-(5-methylthiazol-2-yl)acetamide (CAS 575497-12-0)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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