Brinzolamide Impurity 18 CAS 160982-13-8
| CAS No. | 160982-13-8 |
| Molecular Formula | C10H14ClNO4S2 |
| Molecular Weight | 311.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Brinzolamide Impurity 18 (C10H14ClNO4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 311.81 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Brinzolamide Impurity 18 (CAS 160982-13-8) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14ClNO4S2 and a molecular weight of 311.81 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Brinzolamide Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14ClNO4S2 |
| Molecular Weight | 311.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Brinzolamide Standards
- Brinzolamide Impurity 1 (CAS CATO-C4X-19401)
- Brinzolamide Impurity 7 (CAS CATO-C4X-19407)
- Brinzolamide Impurity 23 (CAS 138890-58-1)
- Brinzolamide Impurity 16 (CAS 171273-35-1)
- Brinzolamide Impurity 26 (CAS CATO-C4X-194026)
- Brinzolamide Impurity 17 (CAS 154127-41-0)
- Brinzolamide Impurity 14 (CAS 154127-42-1)
- Brinzolamide Impurity 15 (CAS 165117-54-4)
Recommended Standards
- tert-Butyl 4-(6-chloro-4-methylpyridin-2-yl)piperazine-1-carboxylate (CAS 2140305-50-4)
- rac-Clopidogrel EP Impurity A-D4 (CAS 1246814-52-7)
- tert-Butyl 4-((6-chloropyridin-3-yl)methyl)piperazine-1-carboxylate (CAS 939986-35-3)
- 7-Chloro-4-methyl-N-(2-morpholinoethyl)benzo[d]thiazol-2-amine (CAS 1105189-47-6)
- Ticagrelor Impurity 77 (CAS CATO-C4X-109377)
- Lomefloxacin Impurity 20 (CAS CATO-C4X-207320)
- Oseltamivir Impurity 92 (CAS 1151665-78-9)
- 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-(3,3,3-trifluoropropyl)-1H-pyrazole (CAS 1809837-98-6)
- 2-((Cyclohexanecarbonyl)oxy)acetic Acid (CAS 667465-00-1)
- (S)-2-((tert-Butoxycarbonyl)amino)-5-(4-(trifluoromethyl)phenyl)pent-4-enoic acid (CAS 1393677-14-9)
- 4-(Chloromethyl)-1-(3,5-dichlorophenyl)-1H-1,2,3-triazole (CAS 1249340-50-8)
- N-(2-Methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyrazin-5-amine (CAS 87594-96-5)
- 3-(4-Butoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 696646-80-7)
- Eledoisin Related Peptide (CAS 2990-43-4)
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