Methyl 2,6-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylate CAS 1610377-18-8
| CAS No. | 1610377-18-8 |
| Molecular Formula | C12H20N2O5Si |
| Molecular Weight | 300.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2,6-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylate is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 2,6-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylate (CAS 1610377-18-8) is a high-purity analytical reference standard with the molecular formula C12H20N2O5Si and a molecular weight of 300.38 g/mol.
Structurally, Methyl 2,6-dioxo-3-((2-(trimethylsilyl)ethoxy)methyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylate (C12H20N2O5Si) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 300.38 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20N2O5Si |
| Molecular Weight | 300.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- N-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448030-03-2)
- 4-((2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl)benzene-1-sulfonyl chloride (CAS 16290-71-4)
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Recommended Standards
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- 3-Methyl-6-(2,4,5-trimethylphenyl)imidazo[2,1-b]thiazole-2-carboxylic acid (CAS 1437434-45-1)
- (3,5-Dimethyl-1H-pyrazol-1-yl)(5-ethyl-2-(1H-pyrrol-1-yl)thiazol-4-yl)methanone (CAS 1707562-55-7)
- 3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-ol (CAS 893738-60-8)
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- 3-Methyl-3-(pyridin-2-yldisulfaneyl)butanoic acid (CAS 107348-49-2)
- Methyl 2-(5-amino-1H-1,2,4-triazol-3-yl)benzoate (CAS 1279813-52-3)
- 2-Chloro-4-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1239876-17-5)
- Dosulepin EP Impurity D (CAS 25846-81-5)
- Flunarizine impurity 47 (CAS 2602342-57-2)
- 5-amino-1-(4-methylbenzenesulfonyl)-2,3-dihydro-1H-pyrazol-3-one (CAS 240117-38-8)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
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