5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid CAS 1612148-85-2
| CAS No. | 1612148-85-2 |
| Molecular Formula | C18H15FN2O4 |
| Molecular Weight | 342.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 1612148-85-2) is a high-purity analytical reference standard with the molecular formula C18H15FN2O4 and a molecular weight of 342.32 g/mol.
Structurally, 5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid (C18H15FN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 342.32 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15FN2O4 |
| Molecular Weight | 342.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 6-(2-(3,4-Dimethoxyphenyl)thiazol-4-yl)picolinic acid (CAS 1027030-15-4)
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Recommended Standards
- 1-[1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo-[3,4-b]pyridin-6-yl]piperidine-4-carboxylic acid (CAS 1308649-27-5)
- (βS)-2-((tert-Butoxycarbonyl)amino)-3-(3-fluoro-4-nitrophenyl)butanoic acid (CAS 2467738-84-5)
- tert-Butyl ((4-phenyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)methyl)carbamate (CAS 1283108-14-4)
- 1-[(2-Fluorobenzyl)oxy]-3-(2-methylbenzyl)-1H-imidazole-2,4,5(3H)-trione (CAS 303986-60-9)
- 3-Chloro-1-phenylisoquinoline (CAS 89721-07-3)
- 3-Iodo-n-methylbenzenesulfonamide (CAS 1144522-75-7)
- N-cyclopropyl-5-(1-tosylpiperidin-2-yl)pyridin-2-amine (CAS 1352498-80-6)
- Ethyl 2-(5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4h)-yl)acetate (CAS 369397-75-1)
- 1-Benzyl-3-(3-bromopropyl)piperidine (CAS 1420966-34-2)
- Olmesartan Impurity 56 (CAS 2347585-74-2)
- 5-Bromo-6-iodo-1,3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 1515384-62-9)
- Lasmiditan Impurity 55 (CAS CATO-C4X-247855)
- 2-(6-Bromo-1H-benzo[d]imidazol-2-yl)acetic acid (CAS 1248666-87-6)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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