6-Chloro-2-((1R)-1-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1-((S)-1,1,1-trifluoropropan-2-yl)-1H-imidazo[4,5-c]pyridine CAS 1612174-31-8
| CAS No. | 1612174-31-8 |
| Molecular Formula | C16H19ClF3N3O2 |
| Molecular Weight | 377.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Chloro-2-((1R)-1-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1-((S)-1,1,1-trifluoropropan-2-yl)-1H-imidazo[4,5-c]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
6-Chloro-2-((1R)-1-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1-((S)-1,1,1-trifluoropropan-2-yl)-1H-imidazo[4,5-c]pyridine (CAS 1612174-31-8) is a high-purity analytical reference standard with the molecular formula C16H19ClF3N3O2 and a molecular weight of 377.79 g/mol.
The molecular framework of 6-Chloro-2-((1R)-1-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)-1-((S)-1,1,1-trifluoropropan-2-yl)-1H-imidazo[4,5-c]pyridine (C16H19ClF3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H19ClF3N3O2 |
| Molecular Weight | 377.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- Amlodipine Impurity 75 (CAS 113994-44-8)
- 2,5-Dibromo-3-iodopyridin-4-amine (CAS 1227268-81-6)
- Cefonicid Impurity 2 (CAS 67146-22-9)
- 2-Chloro-5-(difluoromethyl)anisole (CAS 1261861-85-1)
- 6-(3,5-Difluorophenyl)nicotinaldehyde (CAS 898404-56-3)
- 4-Methyl-3,4-dihydropyrido[2,3-b]pyrazine-1(2H)-carbaldehyde (CAS 138768-67-9)
- 3-Hydroxy-n-(5-methyl-1,3-thiazol-2-yl)benzamide (CAS 1019453-02-1)
- N-(5-chloropyridin-2-yl)cyclopropanecarboxamide (CAS 309290-17-3)
- n-((2-Ethylthiazol-4-yl)methyl)-4-methoxyaniline (CAS 1455761-70-2)
- Bedaquiline Impurity 67 (CAS 345949-37-3)
- 2-((4-(Tert-butyl)benzyl)thio)-3-propyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 860609-19-4)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com