Cis-3-Fluoro-4-Methylpiperidin-4-Ol CAS 1612176-91-6
| CAS No. | 1612176-91-6 |
| Molecular Formula | C6H12FNO |
| Molecular Weight | 133.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cis-3-Fluoro-4-Methylpiperidin-4-Ol.
Cis-3-Fluoro-4-Methylpiperidin-4-Ol (CAS 1612176-91-6) is a high-purity analytical reference standard with the molecular formula C6H12FNO and a molecular weight of 133.16 g/mol.
The molecular framework of Cis-3-Fluoro-4-Methylpiperidin-4-Ol (C6H12FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Cis-3-Fluoro-4-Methylpiperidin-4-Ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12FNO |
| Molecular Weight | 133.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cis Standards
- 6-fluoro-2-methylpyridin-3-ol (CAS 1227577-28-7)
- 3-Fluoro-1-methylpiperidin-4-ol (CAS 1393100-32-7)
- 3-Fluoro-4-methoxypiperidine (CAS 1545253-16-4)
- 3-Fluoro-3-(methoxymethyl)pyrrolidine (CAS 1567070-60-3)
- 3-Fluoro-4-methylpiperidin-4-ol (CAS 1823539-12-3)
- (3-fluoro-1-methyl-1H-pyrrol-2-yl)methanol (CAS 2167647-52-9)
- (R)-(3-Fluoro-1-methylpyrrolidin-3-yl)methanol (CAS 2368910-33-0)
- (S)-(3-Fluoro-1-methylpyrrolidin-3-yl)methanol (CAS 2368910-31-8)
Recommended Standards
- (3S,4S)-3-fluoro-4-methylpiperidin-4-ol (CAS 1612176-04-1)
- 4-(Fluoromethyl)tetrahydro-2H-pyran-4-amine (CAS 1781543-98-3)
- [3-(1-fluoroethyl)oxetan-3-yl]methanamine (CAS 1785359-04-7)
- (3-Fluorotetrahydro-2H-pyran-3-yl)methanamine (CAS 1557978-39-8)
- 2-(4-Acetylphenoxy)-N-phenyl-N-(propan-2-yl)acetamide (CAS 180508-17-2)
- 1-Butyl-2,3,3-trimethyl-3H-indol-1-ium iodide (CAS 20205-30-5)
- 1-Bromo-4-chloro-3-fluoro-2-(fluoromethyl)benzene (CAS 1628524-82-2)
- 5-[(Benzylsulfanyl)methyl]-3-(4-chlorophenyl)-1,2-oxazole (CAS 551921-24-5)
- 1-Bromo-3-(difluoromethyl)-2,5-difluorobenzene (CAS 1807026-02-3)
- n-Ethyl-2-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 565180-73-6)
- (6-Amino-5-methylpyridin-2-yl)methanol (CAS 1807169-17-0)
- 6-(Dimethylamino)pyrimidine-4-carbonitrile (CAS 65735-63-9)
- tert-Butyl 3-(((6-chloropyrimidin-4-yl)amino)methyl)piperidine-1-carboxylate (CAS 939986-78-4)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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