(2e)-3-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]prop-2-enoic acid CAS 1613051-28-7
| CAS No. | 1613051-28-7 |
| Molecular Formula | C12H8FNO2S |
| Molecular Weight | 249.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 249.26 g/mol gives (2e)-3-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]prop-2-enoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (2e)-3-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]prop-2-enoic acid (CAS 1613051-28-7), a certified reference material (molecular formula C12H8FNO2S, MW 249.26 g/mol) for analytical method development and quality control.
(2e)-3-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]prop-2-enoic acid (C12H8FNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2e)-3-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]prop-2-enoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8FNO2S |
| Molecular Weight | 249.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related e Standards
- (4-Fluorophenyl)(4-nitrophenyl)sulfane (CAS 2438-85-9)
- 3-(2-(4-Fluorophenyl)thiazol-4-yl)acrylic acid (CAS 876866-79-4)
- 1-(4-Fluorophenyl)-5-(propan-2-yl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1017470-58-4)
- 3-(1-(3-Fluorophenyl)-3-methyl-1H-1,2,4-triazol-5-yl)propanoic acid (CAS 1142202-58-1)
- 1-(3-Fluorophenyl)-5-(propan-2-yl)-1h-1,2,4-triazole-3-carboxylic acid (CAS 1154371-22-8)
- 1-(2-fluorophenyl)-5-propyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1155460-43-7)
- 1-(2-fluorophenyl)-5-(propan-2-yl)-1H-1,2,4-triazole-3-carboxylic acid (CAS 1155460-50-6)
- 3-(2-Fluorophenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester (CAS 1159600-04-0)
Recommended Standards
- 2-{[(benzyloxy)carbonyl]amino}-2-cyclopropylacetic acid (CAS 159871-55-3)
- 5-Benzyl-7,7-difluoro-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (CAS 1630062-36-0)
- (E)-4-benzylidene-2-phenyloxazol-5(4H)-one (CAS 15732-43-1)
- Ethyl 5,6-dimethoxy-1H-indole-2-carboxylate (CAS 16382-18-6)
- Triphenylmethanesulfenyl Chloride (CAS 24165-03-5)
- 1-(2,5-Difluorobenzyl)azetidin-3-amine (CAS 1483831-55-5)
- [4-bromo-2-(morpholin-4-yl)phenyl]methanol (CAS 1099619-96-1)
- Ethanol, 2-(3,3-dimethylcyclohexylidene)-, (2E)- (CAS 30346-27-1)
- (5-Bromopyridin-3-yl)(4-(4-(thiophen-3-yl)thiazol-2-yl)piperazin-1-yl)methanone (CAS 1448075-21-5)
- 1-Benzyl-4-hydrazinyl-1h-pyrazolo[3,4-d]pyrimidine (CAS 329707-65-5)
- 1-(3-methoxybenzoyl)piperidin-4-one (CAS 1016741-90-4)
- 2-(5-Amino-1H-pyrazol-3-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 1396967-66-0)
- (5-Hydroxynicotinoyl)methionine (CAS 1397007-75-8)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com