1-Methylindole-2-carboxylic Acid CAS 16136-58-6
| CAS No. | 16136-58-6 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Methylindole-2-carboxylic Acid (CAS 16136-58-6) is a high-purity analytical reference standard with the molecular formula C10H9NO2 and a molecular weight of 175.18 g/mol.
1-Methylindole-2-carboxylic Acid (C10H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-Methylindole-2-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Methylindole Standards
- 5-Methylindole-3-carboxylic Acid (CAS 10242-02-1)
- 4-Methylindole-6-carboxylic Acid (CAS 1545472-15-8)
- 4-Methylindole-2-carboxylic Acid (CAS 18474-57-2)
- 6-Methylindole-2-carboxylic Acid (CAS 18474-59-4)
- 4-Methylindole-3-carboxylic Acid (CAS 858515-65-8)
- 6-Methylindole-3-carboxylic Acid (CAS 209920-43-4)
- 1-Methylindole-7-boronic acid (CAS 1443380-07-1)
- 1-Methylindole-3-boronic Acid (CAS 1617547-32-6)
Recommended Standards
- 2-(4-Acetylphenoxy)acetonitrile (CAS 160984-14-5)
- Indole-4-acetic Acid (CAS 16176-74-2)
- 5-Methoxyquinolin-2(1H)-one (CAS 160893-04-9)
- (5-Phenyl-1,2-oxazol-3-yl)methanol (CAS 1619-37-0)
- Ethyl 2-cyano-3-(furan-2-yl)but-2-enoate (CAS 76142-51-3)
- N'-[(1Z)-(4-Methoxyphenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 477864-03-2)
- 2-Bromo-6-nitro-4-trifluoromethyltoluene (CAS 239079-89-1)
- (2-Fluoro-4,5-dimethoxyphenyl)methanol (CAS 79474-33-2)
- methyl 2-methyl-1-(propan-2-yl)-1H-pyrrole-3-carboxylate (CAS 224180-63-6)
- 3-Hydroxy-3-(3-methoxyphenyl)propanenitrile (CAS 103205-23-8)
- 3-(Tert-butoxy)-3-oxopropane-1-sulfinic acid (CAS 77711-07-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(2-methoxyphenyl)thiazol-4-yl)boronate (CAS 2223030-58-6)
- 2-(1-(Sec-butyl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1341072-67-0)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com