2-Chloro-7-methylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one CAS 1613751-74-8
| CAS No. | 1613751-74-8 |
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-7-methylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one (CAS 1613751-74-8), molecular formula C7H6ClN3O and molecular weight 183.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-7-methylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one (C7H6ClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O |
| Molecular Weight | 183.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- 2-Chloro-5-methylfuro[2,3-d]pyrimidin-4-amine (CAS 1607479-44-6)
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- 5-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridin-4(7H)-one (CAS 1602896-54-7)
- 2-Chloro-5-methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 1638771-72-8)
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